Error "ep err: 49" when starting the loader

something prevents the launch of the loader, antivirus (better to remove), the defender of "Windows" (how to disable read here: https://goo.gl/ARBkhd), firewall (how to disable read here: https://goo.gl/HSF2Zf), "Windows SmartScreen" (how to disable read here: https://goo.gl/6tFtz7), maybe third-party programs, try to log in using "VPN", or if you enter with it on the contrary to remove it, also try to reload your router. After the done manipulations, restart the computer.